牛血清白蛋白 来源于牛血清

牛血清白蛋白 来源于牛血清

牛血清白蛋白 来源于牛血清

性质

Related Categories Albumin, Bovine Serum Albumins,Chromatographically Purified, New Zealand Origin Bovine Serum Albumins, 生化试剂,
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biological source   bovine
assay   ≥98% (agarose gel electrophoresis)
form   lyophilized powder
mol wt   ~66 kDa
packaging   poly bottle of
impurities   ≤0.01% free fatty acid (GC)
pH   4.8-7.5
solubility   H2O: soluble 40 mg/mL
storage temp.   2-8°C

折叠

产品描述

包装

1 kg in poly bottle

1, 25, 100 g in poly bottle

Preparation Note

Sourced and manufactured in New Zealand

prepared by chromatography

血清白蛋白可能也会被称为Fraction V。该命名惯例取自使用冷乙醇沉淀对血清蛋白进行分级的原始Cohn法。 血清白蛋白可在采用Cohn′s法的第五乙醇分级中发现。 从此，有些人便开始使用“Fraction V”这一术语来描述血清白蛋白，无论使用的是什么制备方法。 也有人在使用该术语来描述通过乙醇分级方法而纯化得到血清白蛋白，而这种方法是相对于原始的Cohn法一直在得到高度的改良。Sigma-Aldrich生产和分销从各种主要方法纯化得到的血清白蛋白，包括真正的Cohn分级法、改良的乙醇分级方法、热休克和色谱法。 更多的纯化步骤包括结晶或木炭过滤。

Application

Bovine serum albumin (BSA) is extensively used for drug delivery since it is widely available, cheap and easily purified, has ligand-binding properties, and is widely accepted in the pharmaceutical industry. [2]

Biochem/physiol Actions

Albumin is the most important circulatory protein involved in the control of Ca2+ (and Mg2+) levels in mammals. [1]

BSA的某些构象和初级序列表位是人类对牛肉和牛奶过敏中的可疑过敏原。

General description

The most abundant plasma protein in mammals is albumin. It is produced in the liver and transferred as a non-glycosylated protein into the plasma. This multifunctional protein has an amazing ability to bind to ligands. [1]